And I start looking at these two food categories and going, oh, that’s sulfur, that’s not. HT: That I’ve seen, it’s been all of the cases. Now, unfortunately, a lot of these look like histamine responses. And from there, one can progress to maybe a trial of the autoimmune paleo or the paleo low FODMAP, just depending on what they have going on. And after a couple of years of doing that, the Seattle Arthritis Clinic was formed, and I was asked to be a provider there. And I’ve been looking forward to picking her brain. Debunking Histamine Intolerance . I have a lot going on in my life. We might have to supplement from that perspective. You know? We have a nutritionist here. Oxalates can also deposit themselves on the surface of the thyroid itself, contributing to cysts. So it’s a little hard to differentiate between the two. DAO is the enzyme that is primarily responsible for breaking down histamines in the digestive tract of the body. So, we took her off, I identified other sulfur foods, and took her off what I could find. Histamines in Mast Cell Activation Syndrome and Histamine Intolerance You probably know already to avoid high histamine foods when you have Mast Cell Activation Syndrome and Histamine Intolerance. DrMR: And again, the upper level cut off is 40 to be into the positive? All GI tests were fine. DMARDs. And these are all symptoms that I’m describing to you while I’m presenting to you is because, these are all symptoms that I’m seeing being very common among those who have this sulfur intolerance. Because what I’m always trying to do is consolidate to the fewest diets, rather than adding the most nuance and having the highest number of diets. And there’s maybe a slightly elevated oxalate. I’m not really sold that any of those previous diets adequately achieves a low sulfur intake. It’s one of the primary diagnoses that I see. I’d say 90% of people that come in have already tried a gluten free diet and a dairy free diet and they’ve reduced their sugar. They are sulfate. I’ll just say this. DrMR: Awesome. So you have to kind of look at the full picture. Symptoms of Histamine Intolerance. Well, Heidi, thank you so much for taking the time. She had some mast cell issues, but was doing fine with high histamine foods. I have seen some remarkable things for those who do specialize in it, and where I could not get the patients, especially in mast cell issues where I could not get the patient anywhere down the road and they were able to do it. Can you tell people a little bit about your background? According to the American Journal of Clinical Nutrition, histamine intolerance is, “Disequilibrium of accumulated histamine and the capacity for histamine degradation.” Basically, what this says is we’re not necessarily growing more and more sensitive to histamine, we just have too much of it in our bodies. I have it. A new study shows that functional medicine stool testing is inaccurate when it comes to detecting pathogens. And a low oxalate diet, what’s funny. So that encompassed the first 30 years of my life. Like you could do with FODMAPs. I want to take those foods out for a period of time. She did a great presentation on the SIBO, sulfur, and joint rheumatoid arthritis connection. I just haven’t seen it really do anything. Drugs, medical conditions, the environment, nutritional deficiencies, and diet can lead to histamine intolerance. Chocolate, spinach, nuts and seeds (chia, hemp), white potatoes, quinoa, buckwheat, soy, celery, olives, rhubarb, sweet potatoes, and beets are common high oxalate foods. We had been treating her SIBO. DrMR: That’s really where I struggle. I look at the eye inflammation. It’s on everything else, but the food is how I treat. Those have really kind of moved me forward in terms of helping these patients. And I consider those the trifecta. So, with a 42, 41 range. Er zijn veel cellen in het lichaam die al histamine bevatten, als deze cellen geprikkeld worden, dan kan die histamine vrijkomen. I developed chronic allergies towards the end of 2017. Those typically are going to be, they’re good responders to those, basically. Ironically, many patients may be prescribed these medications for symptoms caused by their HIT, if the intolerance has gone unrecognised. So you start there and then you kind of build it yourself, basically, from there. Not just in the diet, but also environmentally. When I do elimination diets, like for gluten and dairy and things like that, I typically see more three weeks on that. The low oxalate diet, open to that. And once those kidneys told us that there was an oxalate issue, we get those oxalates out, her back pain is just, it’s taking months. So totally there with you on that. What do we do to upregulate your ability to manage the sulfur that’s coming through? What you don’t want to do is ask them to do it for too long because really, I look at this as like a little science experiment. Is one of the ones that’s kind of the bottom of the pyramid to consider trying. Fossil fuels. If you suspect oxalates are a problem for you, keep in mind, you do want to reduce your intake very gradually because once you lower your intake a phenomenon called “dumping” will occur which is where oxalates will begin to rapidly exit the tissues, which can cause increased symptoms. Although histamine gets a bad rap, it’s actually a vital neurotransmitter that dilates blood vessels for the immune system for example. Two final questions for you. Doing low histamine. Not so much in the way of fruits. DrMR: I like it! But in a lot of cases it’s not nearly as dire as sometimes people overreact into thinking that it is. No. and if you’re in the Seattle area, I’m at the SeattleArthritisClinic.com. I don’t recommend using it until after a while using molybdenum, to avoid the risk of sulfur overload (which results from sulfur intolerance and the metabolism struggling to process it). HT: No that’s ok. There is the question around whether it’s a sulfur or a thiol issue. So how do we not just reduce the amount of sulfur that’s coming through, but also upregulate the pathways that are going to help you to make that conversion happen. And she’s been doing all of these crazy diets. And whether that is increasing symptoms. So about 10 years ago, I had a patient come in and she – severe – what I noticed in looking. So from there, especially if digestive symptoms are predominant, then you can go to the low FODMAP. So if you’re paleo, you’re going to be taking that way back. And when they go, by the time most people have come in. HT: Constipation. We added Alamax, and we’re going to add in a little NAC as well because, that will help with die off. BreathTests.com is a website for Quintron. You owe me one, so go for it. Although they may be the same in type as an allergic reaction, these symptoms take more time to appear and are not evident immediately after histamine-rich foods and beverages are consumed. That’s R-U-S-C-I-O-20. (3) Amazon and the Amazon logo are trademarks of Amazon.com, Inc, or its affiliates. Dr. Michael Ruscio: Which is why I try, not to cut you off, which is why I remain openminded to the fact that the paleo diet, as healthy as it can be, is not the only healthy diet. HT: Yeah. In 2017, Global Health and Pharma awarded Quintron best in hydrogen and methane breath testing solutions. Okay, back to the show. But we decide, she said, I’ve always felt the best on those antimicrobials. What is that? Histamine is a neurotransmitter naturally produced by the body. If you then, and sorry, Heidi, to be long-winded here. And she has pain that we have not been able to get to, doing anything. Sometimes when people start drifting into too much FODMAP, the come in the clinic, and they go, oh my god. And then I also look at the gut. I look at hormonal fluctuation. I think those are the things that I have seen the most as the contributing factors. One, I already kind of know the answer to, because we were talking about it pre-roll. But sure. The Great 8: Foods for Optimal Thyroid Health. In this post, we will discuss the underlying pathology of the newly demonized phenomenon called histamine intolerance: mast cells, dysbiosis, food poisoning, histamine metabolism/liberators and hormone dysregulation. It’s also is a vital mineral for farming, animals, and people. Do I do SCD? HT: Alright. Her face was swollen. Our Disclaimer and Privacy Policy. What were things we could potentially do? Vegetables. Let’s see, FODMAPs I say two weeks. Within three weeks, a month on that low oxalate diet, she was down to like 20 on her oxalates. She is the former Wellness Coach for the renowned NYTimes bestselling author Amy Myers, M.D. Even though those are not high sulfur. Add it back in, how do I feel. Oxalates are the most acidic organic acid found in bodily fluids and, commercially, are even used to remove rust from car radiators (yikes!). But if the patient hasn’t done it, then absolutely look at those three things. Start from just one perspective and see how you feel. Roughly 1% of the population has histamine intolerance; of those, 80% are middle-aged. Heidi and I first discuss how to efficiently navigate the sea of available diets. So in my mind, the autoimmune paleo diet and the low lectin diet are very similar. So it takes a long time. DrMR: Now, do you find that gastrointestinal symptoms are always present? And I’m also looking at this point at other symptoms that might kind of help me to determine which diet to kind of go with, as well. So I would say, I don’t know. Everything had just swollen up on her, and I didn’t know what was going on. It gives me headaches.” Ok, alright. So you really have to throw, I think, as much as you possibly can at that. Or better yet, use this handy food sensitivity tracker. Some people write to me about having a possible histamine reaction. This article contains scientific references. She had exploded. So, she comes back in a week later, and she had exploded. It is 43, 42-43 I want to say. If you’ve tried every dietary approach, only to be disappointed time and again, this step-by-step program is for you. So she all of a sudden starts getting headaches. DrMR: So, did you say that’s available on your website? And I said, hey! It’s a really significant RA flare when she has it. It controls bodily functions like immune response, mood, sleep, and even helps to secrete gastric juices. Has MCAS, EDS, and the most as the contributing factors back pain, and ’! 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