Anti-Cancer - One natural compound called zerumbone, a cyclic eleven-membered sesquiterpene, isolated from the tropical plant Zingiber zerumbet Smith that has attracted great attention recently for its potent anticancer activities in several tumor models. is an accepted name This name is the accepted name of a species in the genus Zingiber (family Zingiberaceae ). Common Name: Growing plant with developing flower cone at … It is locally known as ‘Lempoyang’ and traditionally used to treat fever, constipation and to relieve pain. ‘Awapuhi is pretty easy to find, as it was a canoe plant, an ancient Polynesian introduction into Hawaii. Mature rhizomes are intensely bitter; young rhizomes are not as powerful. The shoots, rhizomes and inflorescence liquid are all consumable. Anti-Tumor - CXC chemokine receptor 4 (CXCR4), initially linked with leukocyte trafficking, is now known to be expressed in various tumors including breast, ovary, prostate, gastrointestinal, head and neck, bladder, brain, and melanoma. Shampoo Ginger Zingiber zerumbet, is nutrient dense herb support for Cancer, Diarrhea and Dysentery, Hemorrhoid, Fever, Skin Irritation, Cough, Low Blood Pressure, Overcome Swollen Foot after Giving Birth, Treat TBC and Malaria In other words, it can be planted in places where most plants will not live. Type: INDIA: ** Not applicable or data not available. Flowering Plants of Hawaii. 2. Below we consider what are the health benefits of Shampoo Ginger, hopefully adding to our insights into additional information. Milking may be done repeatedly if left on the plant. Zingiber Zerumbet or how the Malay call it "Lempoyang" is a type of perennial herb which can be found in various tropical countries. Zingiber littorale (Valeton) Valeton. Attenuation of Cisplatin-induced hepatotoxicity in rats using zerumbone. Zingiber Zerumbet Smith brought all of it back, and after a lifetime of straight hair actually made it curly and lots thicker. But finally, I got a small bit of rhizome from a neighbor that slowly established itself. Required fields are marked *. From these rhizomes, the plant re-sprouts in spring, when the weather is ideal for them. Zingiber zerumbet (L.) Smith belongs to the Zingiberaceae family that is widely distributed throughout the tropics, particularly in Southeast Asia. Zingiber ovoideum Blume. Terminal (leaf) node. Zérumbet . ZINGIBER ZERUMBET (Linnaeus) Smith, Exot. Simplified isolation, conjugate addition reactions, and a unique ring contracting transannular reaction of its dibromide, Zerumbone inhibits interleukin-6 and induces apoptosis and cell cycle arrest in ovarian and cervical cancer cells, Zerumbone abolishes RANKL-induced NF-κB activation, inhibits osteoclastogenesis, and suppresses human breast cancer–induced bone loss in athymic nude mice, Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the …, Zerumbone, a Southeast Asian ginger sesquiterpene, induced apoptosis of pancreatic carcinoma cells through p53 signaling pathway, Zerumbone inhibits angiogenesis by blocking NF-κB activity in pancreatic cancer, Anticancer activity of natural compound (Zerumbone) extracted from Zingiber zerumbet in human HeLa cervical cancer cells, The chemistry of zerumbone. Articles & Resources . When I first started my garden, I was really interested in finding all the Polynesian canoe plants. This new anticancer bioactive compound from Z. zerumbet was investigated for its activity and mechanism in … The liquid from the inflorescence is drinkable. A lectotypification made by Theilade (Gard. Enter your email address to receive notifications. The rhizomes of Z. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory- and pain-mediated diseases, worm infestation and diarrhea). Zingiber amaricans Blume. from northern India: Potential source of zerumbone rich essential oil for antiproliferative and antibacterial applications, Hepatoprotective Effects of Zerumbone against Paracetamol-Induced Acute Hepatotoxicity in Rats, Immunomodulation of Zerumbone via Decreasing the Production of Reactive Oxygen Species from Immune Cells, Anti-inflammatory Effects of Zerumbone on Chronic Inflammation Models in Differentiated Human THP-1 Monocytes Induced by Lipopolysaccharide, Effects of zerumbone on cisplatin-induced clastogenesis in Sprague-Dawley rats bone marrow cells, Effects of Zerumbone from Zingiber Zerumbet on Cervical Cancer Induced Female Balb/c Mice, Healing potential of zerumbone ointment on experimental full-thickness excision cutaneous wounds in rat, Zerumbone suppresses high glucose-and lipopolysaccharide-induced pro-inflammatory effects through regulation of histone deacetylase in differentiated human THP …, Potential application of zerumbone in the prevention and therapy of chronic human diseases, In Vitro and In Vivo Studies of Pharmacological Effects of Zerumbone on Human Malignant Melanoma, Synthesis and in vitro evaluation of zerumbone pendant derivatives: potent candidates for anti-diabetic and anti-proliferative activities, Zerumbone, a tropical ginger sesquiterpene of Zingiber officinale Roscoe, attenuates α-MSH-induced melanogenesis in B16F10 cells, Molecular Mechanism of the Protective Effect of Zerumbone on Lipopolysaccharide-Induced Inflammation of THP-1 Cell-Derived Macrophages, Influence of Zerumbone Supplementation a Natural Dietary Product from Zingiber zerumbet smith on Early-Developed Atherosclerotic Lesions in Cholesterol …, Abstract P2-09-19: Zerumbone suppresses IL-1b-induced cell migration and invasion through inhibition of IL-8 expression and MMP3 expression in human triple …, Metal‐Free trans‐Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone, Inhibition of metabolic reprogramming by zerumbone alters the tumorigenic potential of hepatocellular cancer, Zerumbone inhibits migration in ESCC via promoting Rac1 ubiquitination, Zerumbone induces G1 cell cycle arrest and apoptosis in cervical carcinoma cells, Production of zerumbone from in vitro derived rhizome of zingiber zerumbet. Zingiber zerumbet: Taxonomy navigation › Zingiber. 4 Aquifoliaceae - Araliaceae - Aristolochiaceae - Asclepiadaceae. so yes ,what is the price + sent cost; Among the benefits of Shampoo Ginger rhizome is as an anti-seizure drug and as a drug to reduce high fever. According to the in vitro study, 1 had greater anti-inflammatory effects than 2. The study investigated the purified zerumbone crystals for its anti-cancer properties on human cervical cancer cell line (HeLa). Zingiber spectabile commonly known as Beehive Ginger is a clumping herbaceous plant native to Peninsular Malaysia and Peninsular Thailand. Contact David Rodriguez to build you one! Also known as bitter ginger, Z. zerumbet is traditionally found throughout Asia, where it is widely used in foods, beverages and for ornamental purposes. The name Z. zerumbet refers to the spreading, antler-like appearance of the stems. It took me awhile before I found my first ‘awapuhi plant. Common names for Zingiber zerumbet include … Also known as bitter ginger, Z. zerumbet is traditionally found throughout Asia, where it is widely used in foods, beverages and for ornamental purposes. 2011). C'est le genre des gingembres véritables dont trois espèces : le gingembre officinal, le gingembre japonais et Zingiber zerumbet sont largement utilisés dans l'alimentation humaine. These findings might suggest possible chemopreventive ability of zerumbone, through suppression of COX-2 expression, cell proliferating activity of colonic mucosa, and induction of phase II detoxification enzymes in the development of carcinogen-induced ACF. Dicot Families . Zingiber spurium J.König. Total synthesis of zerumbone, … cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and …, The chemistry of zerumbone. Cisplatin, was used as a positive control in this study. Part 3: Stereospecific creation of five stereogenic centers by double Sharpless oxidation, Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation, Zerumbone induces apoptosis in human renal cell carcinoma via Gli-1/Bcl-2 pathway, Synthesis of novel zerumbone derivatives via regioselective palladium catalyzed decarboxylative coupling reaction: a new class of α-glucosidase inhibitors, Selective conjugate addition to zerumbone and transannular cyclization of its derivatives, First isolation of sesquiterpenes and flavonoids from Zingiber spectabile and identification of zerumbone as the major cell growth inhibitory component, The effect of pretreatment of zerumbone on fatty liver following ethanol induced hepatotoxicity, Zerumbone increases oxidative stress in a thiol‐dependent ROS‐independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation, Zerumbone Suppresses IL‐1β‐induced Cell Migration and Invasion by Inhibiting IL‐8 and MMP‐3 Expression in Human Triple‐negative Breast Cancer Cells, Antimalarial activity and cytotoxicity of zerumbone derivatives, Antinociceptive and anti-inflammatory effects of zerumbone against mono-iodoacetate-induced arthritis, Lipid-lowering effects of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, in high-fat diet-induced hyperlipidemic hamsters, Evaluation of acute toxicity and the effect of single injected doses of zerumbone on the kidney and liver functions in Sprague Dawley rats. Zingiber darceyi H.J.Veitch. Shoots are spicy and consist of the still folded leaves as they emerge. “Zingiber” is originally from a Sanskrit word that means “shaped like a horn” and refers to the horn-shaped leaves of most species of ginger. my hobby is all 42 year medicinal plants;,have so a 180 sort, as hobby;Iam 82 years old ;Iam looking after these plant ; awapuhi -kuahiwi >>>can jou help: Zingiber zerumbet Amome sauvage . The cytotoxicity of zerumbone and cisplatin were investigated using the MTT assay and caspases-3 was estimated with colorimetric assay in zerumbone treated HeLa cells. 2: 105 1806 . Zingiber zerumbet is widely used as therapeutic agent in traditional medicine and is reported to exert antioxidant activities. It originates from Asia, but can be found in many tropical countries. Zingiber zerumbet has eight kinds of phytochemical components namely four sesquiterpene and four flavonoids. The authority listed in The Plant List (2013) is Zingiber zerumbet (L.) Roscoe ex Sm. Plant List . Phytochemistry 30(7):2391–2392 Google Scholar. Zingiber zerumbet (L.) Roscoe ex Sm., Zingiberaceae, is a perennial, aromatic and tuberose plant that grows in humid locations. The type for Z. zerumbet is still to be sought among several syntypes. Matthes HWD, Luu B, Ourison G (1980) … These findings support the use in Thai traditional medicine of these selected Zingiberaceous plants, especially Kaempferia parviflora and Zingiber cassumunar, for treatment of allergy and allergic-related diseases. 004 cone gingers.jpg 574 × 480; 104 KB. A Floridata plant profile of species Zingiber zerumbet, commonly called pinecone ginger, shampoo ginger, Awapuhi kuahiwi (Hawaii) Home . Bot. Therefore, mice were administered with 1 (10 mg/kg) 1 h before carrageenan injection, and the oedema was significantly attenuated compared to the vehicle control. Zingiber Zerumbet-Smith brought all of it back, and after a lifetime of straight hair actually made it curly and lots thicker. 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Zerumbone suppresses osteopontin-induced cell invasion through inhibiting the FAK/AKT/ROCK pathway in human non-small cell lung cancer A549 cells, Zerumbone, a phytochemical of subtropical ginger, protects against hyperglycemia-induced retinal damage in experimental diabetic rats, Zerumbone protects INS-1 rat pancreatic beta cells from high glucose-induced apoptosis through generation of reactive oxygen species, Anticancer activity of the bioreductive and non-bioreductive zerumbone derivatives, Zerumbone inhibits melanoma cell proliferation and migration by altering mitochondrial functions, Development and validation of an HPTLC method for analysis of zerumbone, the anticancer marker from Zingiber zerumbet, Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-β1 signaling pathway, Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between …, Promotion of p53 expression and reactive oxidative stress production is involved in zerumbone-induced cisplatin sensitization of non-small cell lung cancer cells, Protective effect of zerumbone reduces lipopolysaccharide-induced acute lung injury via antioxidative enzymes and Nrf2/HO-1 pathway, Inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin induces apoptosis in liver hepatocellular HepG2 cells via caspase 8/bid cleavage switch and …, Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone, Zerumbone suppresses EGF-induced CD44 expression through the inhibition of STAT3 in breast cancer cells, A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes, Contribution to the Study of Essential Oil of Xylopia Aethiopica (DUNAL) A. It can be concluded that, potent antibacterial and antifungal phytochemicals are present in ethanol extract of Z. zerumbet (L). Contact Gavin Robert McGowen Here, Join the following facebook groups to learn more: Ultimate Weightloss Challenge , Dry Fasting, Longevity Agents , Interstellar Blend Seven Sages, The Infinitely Postive, THE INTERSTELLAR BLEND CHALLENGE: Fluid Restricted Fasting w/ Superherbs. This review summarizes the data based on various in vitro and in vivo studies related to the effects of zerumbone on numerous pivotal molecular targets in cancer and its reported chemopreventive/therapeutic effects in different models of cancer. : it’s generally not a problematic plant). Zingiber truncatum Stokes. Pinecone ginger grows in USDA zones 8 through 11. Pinecone ginger (Zingiber zerumbet), which is also sometimes called shampoo ginger, produces showy, pinecone-shaped flower bracts. Zingiber zerumbet (L.) Roscoe ex Sm., Zingiberaceae, is a perennial, aromatic and tuberose plant that grows in humid locations. Anti-Inflammatory - In this paper, zerumbone (1), 3-O-methyl kaempferol (2), kaempferol-3-O-(2, 4-di-O-acetyl-α-l-rhamnopyranoside) (3), and kaempferol-3-O-(3,4-di-O-acetyl-α-l-rhamnopyranoside) (4) were isolated from the rhizome of Z. zerumbet. Origine: Originaire d'Asie. © 2020 Interstellar Blends | Activate Your Super Powers!. This ginger relative grows to heights of about two to four feet. Two years later, I was able to dig up that original clump and spread it around to create many more plants, some of which I planted in a waterway where not many other plants want to grow. Common names include: awapuhi, bitter ginger, shampoo ginger (Malay = lempoyang) and pinecone ginger. J Essent Oil Res 5(1):55–59 Google Scholar. The name Zingiber actually stems from a Sanskrit word which means a Bull's Horn. Introduction. Notify me of follow-up comments by email. For a few months, I was confused about that whole situation until I allowed some of the rhizomes he gave me to grow out. L'utilisation la plus commune du Zingiber zerumbet est en soin capillaire comme shampooing ou conditionneur. The conformational mobility of humulene and zerumbone, In vitro covalent binding proteins of zerumbone, a chemopreventive food factor, Zerumbone inhibits tumor angiogenesis via NF-κB in gastric cancer, Chemistry of zerumbone. is an important monocotyledonous plant belonging to Zingiberaceae commonly known as shampoo ginger or pinecone ginger. Pinecone ginger typically grows to about 7 feet tall, but varieties such as “Darceyi” (Zingiber zerumbet “Darceyi”) are smaller, reaching only about 4 feet. In this study, we report the identification of zerumbone, a component of subtropical ginger (Zingiber zerumbet), as a regulator of CXCR4 expression. To utilize the liquid from the inflorescence: use a cup or jar and hand-squeeze the inflorescence until the juice comes out. Zingiber blancoi Hassk. Zerumbone induces heme oxygenase-1 expression in mouse skin and cultured murine epidermal cells through activation of Nrf2, Immunomodulatory effects of zerumbone isolated from roots of Zingiber zerumbet, Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis, Zerumbone suppresses phorbol ester-induced expression of multiple scavenger receptor genes in THP-1 human monocytic cells, Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trials, Zerumbone, a tropical ginger sesquiterpene, ameliorates streptozotocin-induced diabetic nephropathy in rats by reducing the hyperglycemia-induced …, Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis, Attenuation of cisplatin-induced nephrotoxicity in rats using zerumbone, Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice, Antisecretory, gastroprotective, antioxidant and anti-helicobcter pylori activity of zerumbone from Zingiber Zerumbet (L.) Smith, Dietary zerumbone prevents against ultraviolet B-induced cataractogenesis in the mouse, Dietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-κB, iNOS, and TNF-α expression and reduction of MDA …, Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia …, Zerumbone isolated from Zingiber zerumbet inhibits inflammation and pain in rats, Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells, Molecular cloning and functional characterization of α-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet …, Zerumbone exerts a beneficial effect on inflammatory parameters of cholecystokinin octapeptide-induced experimental pancreatitis but fails to improve histology, Crystal structure of zerumbone [(E, E, E)-2, 6, 9, 9-Tetramethylcycloundeca-2, 6, 10-trien-1-one], Unprecedented olefin-dependent histidine–kinase inhibitory of zerumbone ring-opening material, Zerumbone causes Bax-and Bak-mediated apoptosis in human breast cancer cells and inhibits orthotopic xenograft growth in vivo, Optimization of SC–CO2 extraction of zerumbone from Zingiber zerumbet (L) Smith, Regression of cervical intraepithelial neoplasia by zerumbone in female Balb/c mice prenatally exposed to diethylstilboestrol: involvement of mitochondria-regulated …, Zerumbone attenuates the severity of acute necrotizing pancreatitis and pancreatitis-induced hepatic injury, Zerumbone exerts antiproliferative activity via apoptosis on HepG2 cells, Transannular cyclizations of zerumbone epoxide, High content of zerumbone in volatile oils of Zingiber zerumbet from southern India and Malaysia, Zerumbone, an electrophilic sesquiterpene, induces cellular proteo-stress leading to activation of ubiquitin–proteasome system and autophagy, Hepatoprotective action of zerumbone against paracetamol induced hepatotoxicity, Zerumbone inhibits growth of hormone refractory prostate cancer cells by inhibiting JAK2/STAT3 pathway and increases paclitaxel sensitivity, Chondroprotective effect of zerumbone on monosodium iodoacetate induced osteoarthritis in rats, Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells, Exploring the immunomodulatory and anticancer properties of zerumbone, Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model, Altered cross-linking of HSP27 by zerumbone as a novel strategy for overcoming HSP27-mediated radioresistance, In vivo and In vitro Genotoxic Effects of Zerumbone, Comparative study on inhibitory activity of zerumbone and zerumbone 2, 3-epoxide on NF-κB activation and NO production, Combination of zerumbone and cisplatin to treat cervical intraepithelial neoplasia in female BALB/c mice, Remarkable synthesis and structure of allene type zerumbone, Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics, Acute toxicity study of zerumbone-loaded nanostructured lipid carrier on BALB/c mice model, Synthesis of a novel inhibitor against MRSA and VRE: preparation from zerumbone ring opening material showing histidine-kinase inhibition, Synthesis of macrocyclic terpenoids by intramolecular cyclization. This study showed promising avenues towards zerumbone to be developed as a new chemo-natural drug for treatment of cervical cancer. The record derives from WCSP (data supplied on 2012-03-26 ) which reports it as an accepted name (record 273442 ) with original publication details: Exot. Plant it, let it grow and watch the flowers emerge. USES: Ginger has been used for stomach upset, motion sickness, nausea, and vomiting.Some herbal/ diet supplement products have been found to contain possibly harmful impurities/additives. 2: 105, t. 112. Save my name, email, and website in this browser for the next time I comment. They are grown as ornamentals and their leaves are used in cuisine and traditional medicine. Also see: Which Foods Have More Vitamin C . Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials: A Review, Antiproliferative and antiangiogenic effects of zerumbone from Zingiber zerumbet L. Smith in sprague dawley rat model of hepatocellular carcinoma, Zerumbone Induces Apoptosis in Breast Cancer Cells by Targeting αvβ3 Integrin upon Co-Administration with TP5-iRGD Peptide, INHIBITORY EFFECT OF ZERUMBONE ON MIGRATION OF COLORECTAL CANCER CELLS VIA DOWN-REGULATION OF MATRIX METALLOPROTEINASE-13 …, Molecular docking, MD simulation, DFT and ADME-toxicity study on analogs of zerumbone against IKK-β enzyme as anti-cancer agents, Prophylactic and Therapeutic Efficacies of Dietary Zerumbone Supplementation on the Pathogenesis of Atherosclerosis in Cholesterol-fed Rabbits, ANTI-LEUKEMIC EFFECTS OF ZERUMBONE NANOPARTICLE ON HUMAN LYMPHOBLASTIC LEUKEMIA CELLS (JURKAT) IN VITRO AND MURINE …, Lewis-Acid-Catalyzed Activation of Zerumbone towards Sesquiterpenoid Derivatives: Sustainable Utilization of Abundant Natural Resources for the Synthesis of …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC PROPERTIES OF ZERUMBONE AND THEIR MECHANISMS OF ACTION IN MICE MODEL OF NEUROPATHIC …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF ZERUMBONE THROUGH INVOLVEMENT OF MONOAMINERGIC PATHWAYS IN MICE MODEL …, COMPARISON STUDY OF THE EFFECTS OF ZERUMBONE AND AG490 IN HUMAN RENAL CELL CARCINOMA ON THE ACTIVATION OF THE JANUS KINASE …, CYTOTOXICITY AND MECHANISMS OF ACTION OF ZERUMBONE-LOADED NANOSTRUCTURED LIPID CARRIER IN TRIPLE NEGATIVE BREAST CANCER …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC ACTIVITIES OF ZERUMBONE IN CHRONIC CONSTRICTION INJURY-INDUCED NEUROPATHIC PAIN AND …, Potential chemoprevention of dimethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the …, … Obat Antikanker Payudara dari Lempuyang Gajah dan Lempuyang Emprit dengan Kontrol Kualitas Berbasis Senyawa Penanda Zerumbone dan Aktivitas Antikanker …, Zerumbone Protects against Carbon Tetrachloride (CCl4)-Induced Acute Liver Injury in Mice via Inhibiting Oxidative Stress and the Inflammatory Response: Involving …, … of ATF3 for ER Stress-induced Sensitization of p53-deficient Human Colon Cancer Cells to TRAIL-mediated Apoptosis Through Upregulation of DR5 by Zerumbone …, Study on transformation of zerumbone with fatty acid hydrazides, Hormetic Effects of Zerumbone in Proteostasis, Zerumbone 처리에 따른 Helicobacter pylori 의 단백질 비교분석, CYTOTOXICTY OF ZERUMBONE AGAINST LIVER CANCER CELL LINES (HepG2) VIA APOPTOSIS ACTIVITY, Comparative Proteome Analysis of Zerumbone-treated Helicobacter pylori, Nghiên cứu các phương pháp phân lập Zerumbone có chất lượng cao từ thân rễ cây gừng gió (zingiber zerumbert sm.) Abstract. The leaves can be purple located beneath the young shoots and are rather thin and around 25-35cm in length. 1. We suggest that the economic cultivation period of Z. zerumbet is the 5th month after seeding when its functions as food and anti-inflammatory are maximum, because 1 is dramatically increased at that time. The viscous juice present in the inflorescence of the plant is rich in surfactants and is also known as … 3 Apiaceae - Apocynaceae. Results show that zerumbone is a novel inhibitor of CXCR4 expression and thus has a potential in the suppression of cancer metastasis. Zingiber sylvestre Garsault. In the next study they assessed the effects of zerumbone on cell proliferation activity of crypts by counting silver-stained nucleolar organizer regions protein (AgNORs) in colonic cryptal cell nuclei. 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